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Celiac Research Needs You

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Celiac Research Needs You Celiac Research Needs You

Celiac Research Needs You






According to legend, celiac research originated with Dr. Willem Dicke. He discovered the cause of celiac during the 1944-?45 Dutch famine under German occupation. He noticed children recovering on a starvation diet, then falling sick after bread was airdropped into Holland. Dicke conducted clinical trials for years, asking parents to remove one food or another from their children?s diets. The famine confirmed what he already knew: something in wheat, barley and rye was the culprit.
?That was one of the huge breakthroughs in celiac disease: identifying an environmental factor that drives the immune disease,? says Ciarán Kelly, MD, medical director of the celiac center at Beth Israel Deaconess Medical Center in Boston. ?With most autoimmune diseases, we do not know what the environmental factor is.?
Celiac offers a unique tool to study autoimmunity, explains Daniel Leffler, MD, director of clinical research at the celiac center: ?We can control celiac disease by adding and removing gluten in a so-called gluten challenge study, a degree of control we have in very few other diseases.?
Celiac often killed children before Dicke solved the puzzle. Now most patients live full, healthy lives on a gluten-free diet.
However, not everyone recovers well. Strict gluten avoidance affects quality of life. Inability to follow the diet or accidental gluten exposure?getting ?glutened??can cause ongoing symptoms. In refractory celiac disease, intestinal damage persists despite strict adherence...
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Source of the new: Gluten free living
Publication date: 02-05-2018 14:45
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